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MerckTakesPatient-DirectedApproachtoBringInnovationtotheTreatmentofRareNeuromuscularDisorder,GeneralizedMyastheniaGravis
===2025/11/25 10:14:49===
phone-based functional tests, and electronic patient-reported outcomes (ePROs) could detect changes in disease trajectory in real-world conditions.

The MyClad trial (NCT06463587) is a global Phase 3, randomized, double-blind and placebo-controlled study designed to assess the efficacy and safety of cladribine capsules in 264 patients with gMG. Cladribine is proposed to target selectively the B and T cells believed to contribute to the production of harmful autoantibodies that cause inflammation and damage to the neuromuscular junction. This mechanism of action, combined with a short-course infrequently-administered oral regimen taken at home, that if approved, may help reduce the burden of the disease by addressing its underlying cause.

Merck will announce results from the MyClad trial following its completion and remains committed to ongoing collaboration with the gMG community to ensure patient needs continue to guide clinical developments.

About generalized Myasthenia Gr
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