bining the power of both NASHA®and OBT within the Restylane portfolio in Japan, physicians can tailor treatments more precisely than ever before. This broader set of tools supports naturallooking, expressive outcomes and aligns Japan with international best practice.”



DR. STEPHANIE LAM

PLASTIC SURGEON, CENTRAL HEALTH MEDICAL PRACTICE

HONG KONG










The Restylane portfolio in Japan now includes four products in total, with Refyne and Defyne joining NASHA-powered products, Restylane Classyc™and Restylane Lyft™.1-4This versatile range enables clinicians to meet diverse patient needs, from soft, flexible formulations that smooth fine lines, to firmer gels that deliver contouring and support.1-7,12,13

The approvals of Restylane Refyne and Defyne in Japan were based on two pivotal, double-blinded, randomized
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