TakedaandProtagonistAnnounceU.S.FoodandDrugAdministrationAcceptsNewDrugApplicationandGrantsPriorityReviewforRusfertideasaPotentialFirst-in-ClassTherapyforPolycythemiaVera
===2026/3/2 17:48:45===
for development in Phase 2 and beyond.
Rusfertide is a first-in-class hepcidin mimetic peptide that is being co-developed with Takeda Pharmaceuticals pursuant to a worldwide license and collaboration agreement entered in 2024. Protagonist holds an option to co-commercialize rusfertide in the U.S. through a 50/50 profit and loss share structure or can opt-out of this structure. The Company also has a number of preclinical stage drug discovery programs addressing clinically and commercially validated targets including an oral IL-17 peptide antagonist, obesity dual and triple agonists, an oral hepcidin functional mimetic, and the recently announced IL-4 and amylin programs.
More information on Protagonist, its pipeline drug candidates, and clinical studies can be found on the Company's website athttps://www.protagonist-inc.com.
Takeda Important Notice
For the purposes of this notice, “press release” means this document, any oral presenta
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