AAD2026:Late-BreakingNemolizumabDataDemonstrateClinicallyMeaningfulBenefitsforChildrenAged2to11WithModerate-to-SevereAtopicDermatitis
===2026/3/30 11:39:27===
with adults and adolescents.”
LAWRENCE EICHENFIELD, M.D.
PROFESSOR OF DERMATOLOGY AND PEDIATRICS AT THE UNIVERSITY OF CALIFORNIA SAN DIEGO SCHOOL OF MEDICINE AND CHIEF OF PEDIATRIC DERMATOLOGY ATRADY CHILDREN'S HOSPITAL SAN DIEGO, UNITED STATES
Clinically meaningful reductions in skin lesions and itch in children with atopic dermatitis
A phase II study (NCT04921345) was conducted to assess the pharmacokinetics, safety, and efficacy of nemolizumab in children (aged 2 to 11 years) with moderate-to-severe atopic dermatitis.1Results showed that nemolizumab pediatric doses were associated with similar pharmacokinetic exposure compared to adults and adolescents, and were well tolerated and effective in children, with clinically meaningful reductions in skin lesions and itch through Week 16 and sustained up to Week 52.1Amongst two of the cohorts evaluated, children aged 7 to 11 and 2 to 6, with nemolizumab doses of 5 mg (for weights ≥10 kg to <20
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