InterimDataFromTwoOngoingInvestigator-initiatedTrialsHighlighttheRoleofSculptraandRestylaneinAddressingAestheticChangesAssociatedWithWeightLossMedicationsandMenopause
===2026/4/9 14:11:32===
t loss.2The IIT, conducted by Dr. Sabrina Fabi, evaluated 20 female patients with mild-to-moderate skin laxity on their abdomen.2
Interim results demonstrated a statistically significant, fourfold reduction in adiposederived stem cells (ADSCs), the regenerative cell population responsible for maintaining healthy fat tissue, when compared to those who were not taking prescription weight loss medication.2Fibroblasts were preserved. These findings contribute to a broader understanding of how the skin profile in individuals experiencing aesthetic changes associated withmedication-driven weight loss differs from those where changes are occurring naturally with age without having taken prescription weight loss medications, and highlight why patients may benefit from treatment plans that focus not just on replacing lost volume, but on supporting the tissues’ underlying regenerative capacity.2,13Galderma is wellpositioned to address these alterations across the face and body, g
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