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1



World Health Organization Colorectal cancer: Key facts. Accessed 8 May 2026. https://www.who.int/news-room/fact-sheets/detail/colorectal-cancer.





2



Kopetz S BV, et al. M9140, a novel anti-CEACAM5 antibody–drug conjugate with a potent topoisomerase 1 inhibitor payload (exatecan): preclinical data and results from a phase 1 dose-escalation study in patients with metastatic colorectal cancer (PROCEADE-CRC-01). Natu
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