GaldermaReceivesU.S.FDAApprovalforDifferin庐Epiduo庐AcneGelPrescription-to-OTCSwitch
===2026/5/26 0:28:20===
BILL ANDRIOPOULOS, PH.D.
HEAD OF GLOBAL MEDICAL AFFAIRS
GALDERMA
Clinical data supporting the approval demonstrated:
Proven efficacy across multiple randomized, controlled Phase 3 studies, with adapalene/benzoyl peroxide gel consistently outperforming adapalene alone, benzoyl peroxide alone, and vehicle gel across inflammatory, non-inflammatory, and total acne lesions, as well as Investigator Global Assessment (IGA) success rates (“clear” or “almost clear”).3-5
Clinically meaningful improvement in lesion counts seen as early as Week 1, with antimicrobial activity beginning on Day 1 and up to 70.3% reduction in inflammatory acne lesions at Week 12.3
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